Pilot trial of inosine to elevate urate levels in amyotrophic lateral sclerosis

Katharine Nicholson, James Chan, Eric A. Macklin, Mark Levine‐Weinberg, Christopher Breen, Rachit Bakshi, Daniela L. Grasso, Anne‐Marie Wills, Samad Jahandideh, Albert A. Taylor, Danielle Beaulieu, David L. Ennist, Ovidiu Andronesi, Eva‐Maria Ratai, Michael A. Schwarzschild, Merit Cudkowicz, Sabrina Paganoni

Published online in Annals of Clinical and Translational Neurology on October 22, 2018

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Poster: The Proper Use of Historical Controls in ALS Trials

Presented at the 27th International Symposium on Amyotrophic Lateral Sclerosis and Motor Neurone Disease, Dublin Ireland, December 2016. Objectives: We asked, for what types of ALS human clinical trials can concurrent controls, historical controls, and virtual...

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